: Low-grade inflammation is present in some cases of schizophrenia, particularly in
the early stages of this disorder. The inflammation source is not known but may be
the result of dysbiotic processes occurring in the gut. We examined peripheral biomarkers
of bacterial translocation, soluble CD14 (sCD14) and lipopolysaccharide binding protein
(LBP), and of general inflammation, C-reactive protein (CRP), in a unique, pre-onset
study of schizophrenia. This sample was composed of 80 case-control matched pairs
of US military service members from whom blood samples were obtained at time of entry
to service, before a psychiatric diagnosis was made.
the early stages of this disorder. The inflammation source is not known but may be
the result of dysbiotic processes occurring in the gut. We examined peripheral biomarkers
of bacterial translocation, soluble CD14 (sCD14) and lipopolysaccharide binding protein
(LBP), and of general inflammation, C-reactive protein (CRP), in a unique, pre-onset
study of schizophrenia. This sample was composed of 80 case-control matched pairs
of US military service members from whom blood samples were obtained at time of entry
to service, before a psychiatric diagnosis was made.
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